Everything about Atpenin A5
Everything about Atpenin A5
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carbamazepine will lessen the level or impact of bortezomib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
bortezomib will raise the amount or effect of clobazam by impacting hepatic enzyme CYP2C19 metabolism. Use Warning/Keep track of. Dosage adjustment can be needed; CYP2C19 inhibitors may possibly bring about improved exposure to N-desmethylclobazam (Energetic metabolite).
triclabendazole will improve the level or influence of bortezomib by affecting hepatic enzyme CYP2C19 metabolism.
ponesimod and bortezomib both of those increase immunosuppressive effects; threat of an infection. Use Caution/Monitor. Caution if coadministered on account of additive immunosuppressive effects in the course of these types of therapy and Lp-PLA2-IN-1 while in the months pursuing administration.
ketoconazole will enhance the level or impact of bortezomib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
apalutamide will decrease the level or outcome of bortezomib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Coadministration of apalutamide, a robust CYP3A4 inducer, with medication which have been CYP3A4 substrates can result in decrease publicity to those medications.
nevirapine will lessen the extent or influence of bortezomib by impacting hepatic/intestinal enzyme Lenvatinib CYP3A4 metabolism. Use Caution/Keep an eye on.
deferasirox will decrease CP-866087 the extent or result of bortezomib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
apalutamide will minimize the level or impact of bortezomib by influencing hepatic enzyme CYP2C19 metabolism. Prevent or Use Alternate Drug. Coadministration of apalutamide, a robust CYP2C19 inducer, with medicines which can be CYP2C19 substrates can result in lessen exposure to those prescription drugs.
Cancer remedy options are unique to every patient. In case you are a affected individual, please speak with your Health care workforce to know how this information and facts relates to you.
bortezomib will improve the level or influence of mavacamten by affecting hepatic enzyme CYP2C19 metabolism. Contraindicated. Solid or moderate CYP2C19 inhibitors may well boost mavacamten systemic publicity, causing heart failure resulting from systolic dysfunction.